Phospho-PML Protein (Ser518) Rabbit mAb

263187

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263187

Product Name: Anti-Phospho-PML Protein (Ser518) Rabbit Monoclonal Antibody

Synonyms: PML; MYL; RNF71; TRIM19; Protein PML; Promyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19

UNIPROT ID: P29590

Background: Regulates RB1 phosphorylation and activity. Required for normal development of the brain cortex during embryogenesis. Can sequester herpes virus and varicella virus proteins inside PML bodies, and thereby inhibit the formation of infectious viral particles. Regulates phosphorylation of ITPR3 and plays a role in the regulation of calcium homeostasis at the endoplasmic reticulum (By similarity). Regulates transcription activity of ELF4.

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser518 of human PML Protein

Applications: WB,IHC-P

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R01-3D1

MW: Calculated MW: 98 kDa; Observed MW: 98,117 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Phosphorylated

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Epigenetics and Nuclear Signaling

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using PML Protein (Phospho-Ser518) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Phospho-PML Protein (Ser518) in A549, HL-60, U2OS lysates using Phospho-PML Protein (Ser518) antibody.

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Phospho-PML Protein (Ser518) Rabbit mAb

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