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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N263196 |
Product Name: Anti-Phospho-Smad1 (Ser463/Ser465) Rabbit Monoclonal Antibody |
Synonyms: SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein |
UNIPROT ID: Q15797 |
Background: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. |
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser463/Ser465 of human Smad1 |
Applications: WB,IP |
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R07-4A3 |
MW: Calculated MW: 52 kDa; Observed MW: 52 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Human,Rat |
Conjugation: Unconjugated |
Modification: Phosphorylated |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Signal Transduction |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of Phospho-Smad1 (Ser463/Ser465) in A549, U2OS, C6 lysates using Phospho-Smad1 (Ser463/Ser465) antibody. |
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