Daxx Rabbit mAb

263297

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263297

Product Name: Anti-Daxx Rabbit Monoclonal Antibody

Synonyms: DAXX; BING2; DAP6; Death domain-associated protein 6; Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated protein

UNIPROT ID: Q9UER7

Background: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted.

Immunogen: A synthetic peptide of human Daxx

Applications: WB,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R07-7F4

MW: Calculated MW: 81 kDa; Observed MW: 110 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Daxx in HepG2, U251, HL-60 lysates using Daxx antibody.

Immunocytochemistry analysis of Daxx (green) in K562 using Daxx antibody,and DAPI(blue).

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Product Categories

Daxx Rabbit mAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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