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IL-1 Receptor Accessory Protein Rabbit mAb

263383

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263383
Product Name:   Anti-IL-1 Receptor Accessory Protein Rabbit Monoclonal Antibody
Synonyms:   IL-1 Receptor Accessory Protein; IL1R3; C3orf13; IL-1RAcP
UNIPROT ID:   Q9NPH3
Background:    Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
Immunogen:    Recombinant protein of human IL-1RAcP
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-3B8
MW:    Calculated MW: 65 kDa; Observed MW: 78 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of IL-1RAcP in HL-60, U251, U87-MG lysates using IL-1 Receptor Accessory Protein antibody.
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