p57 Kip2 Rabbit mAb

263479

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263479

Product Name: Anti-p57 Kip2 Rabbit Monoclonal Antibody

Synonyms: CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2

UNIPROT ID: P49918

Background: p27 Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators.

Immunogen: A synthetic peptide of human p57 Kip2

Applications: WB,IHC-P,IP

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R07-8B7

MW: Calculated MW: 32 kDa; Observed MW: 57 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p57 Kip2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of p57 Kip2 in A549, U2OS lysates using p57 Kip2 antibody.

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