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SV40 T Antigen Rabbit mAb

263567

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263567
Product Name:   Anti-SV40 T Antigen Rabbit Monoclonal Antibody
Synonyms:   Large T antigen; LT; LT-AG
UNIPROT ID:   P03070
Background:    Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.
Immunogen:    A synthetic peptide of SV40 T-antigen
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-7D4
MW:    Calculated MW: 82 kDa; Observed MW: 90 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    All
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Infectious Diseases
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of SV40 Tantigen (green) in hela using SV40 Tantigen antibody,and DAPI(blue)

Western blot analysis of SV40 Tantigen in A549, HL-60, U251 lysates using SV40 T Antigen antibody.
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