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q(Q209L)

26328

Size:100 μl Price:$ 495 Brand:NewEast Place of Origin:USA Immunogen:

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q(Q209L)

Cat. #:  26328
Gene Symbol:  GNAQ, CMC1, G-ALPHA-q, GAQ, SWS
Description:   Anti-GNAQ(Q209L) Mouse Monoclonal Antibody
Background:   GNAQ is a protein that in humans encoded by the GNAQ gene. The GNAQ protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospholipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation.
Immunogen:   A synthetic peptide from the internal region of GNAQ which includes the mutation of Q209L, human origin.
Applications:   ELISA, IF, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes Gαq(Q209L) mutant, but not wild type Gαq of vertebrates.
Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence:  

Western blot analysis of recombinant GNAQ(Q209L) and wild type proteins. Purified His-tagged GNAQ(Q209L) protein (lane 2) and corresponding wild type protein (lane 1) were blotted with anti-GNAQ(Q209L) monoclonal antibody (Cat. # 26328).

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