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PD-1 (DM177) Rabbit mAb

28520

Size:100 μg Price:$ 445 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   28520
Product Name:   Anti-PD-1(DM177) Rabbit Monoclonal Antibody
Synonyms:   PDCD1; PD1; CD279; SLEB2
Description:    Anti-PD-1 antibody(DM177) Rabbit Monoclonal Antibody
Background:    This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice; expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB:c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human PD-1
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-PD-1 (DM177) on Expi293 cells transfected with human PD-1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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