CEACAM5 (DM120) Rabbit mAb

28465

Size：100 μg Price：$ 445 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 28465

Product Name: Anti-CEACAM5(DM120) Rabbit Monoclonal Antibody

Synonyms: CEACAM-5;CD66e;CEA;Meconium antigen 100

Description: Anti-CEACAM5 antibody(DM120) Rabbit Monoclonal Antibody

Background: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally; the encoded protein may regulate differentiation; apoptosis; and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.

Applications: ELISA; Flow Cyt

Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100

Host Species: Rabbit

Isotype: Rabbit IgG

Purification: Purified from cell culture supernatant by affinity chromatography

Species Reactivity: Human CEACAM5

Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human CEACAM5 protein, His tagged protein 11194 can bind Rabbit anti-CEACAM5 monoclonal antibody (clone: DM120) in a linear range of 0.1-50 ng/ml.

Figure 2. Flow cytometry analysis with Anti-CEACAM5 (DM120) on Expi293 cells transfected with human CEACAM5(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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