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Trop2 (DM74) Rabbit mAb

28389

Size:100 μg Price:$ 445 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   28389
Product Name:   Anti-Trop2(DM74) Rabbit Monoclonal Antibody
Synonyms:   TACSTD2; GA733-1; M1S1; TROP2
Description:    Anti-Trop2 antibody(DM74) Rabbit Monoclonal Antibody
Background:    This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human Trop2
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human Trop2 protein, mFc-His tagged protein 11304 can bind Rabbit anti-Trop2 monoclonal antibody  (clone: DM74) in a linear range of 1-100 ng/ml.

Figure 2. Expi 293 cell line transfected with irrelevant protein  (A) and human Trop2  (B) were surface stained with Rabbit anti-Trop2 monoclonal antibody 1µg/ml  (clone: DM74) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody
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