IL6 Rabbit pAb

215106

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S215106

Product Name: Anti-IL6 Rabbit Polyclonal Antibody

Synonyms: CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2

UNIPROT ID: P05231 (Gene Accession - NP_000591 )

Background: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).

Immunogen: Synthetic peptide of human IL6

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-100;WB: 500-2000;ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Immunology, Neuroscience, Microbiology, Cancer, Metabolism

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 215106(IL6 Antibody) at a dilution of 1/50(Secreted).	In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 215106(Anti-IL6 Antibody) at dilution 1/50.
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 215106(Anti-IL6 Antibody) at a dilution of 1/50.	In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D162892(Anti-IL6 Antibody) at dilution 1/50.
Gel: 12%SDS-PAGE, Lysate: 40 μg; Lane: K562 cell lysate; Primary antibody: 215106(IL6 Antibody) at dilution 1/800; Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution; Exposure time: 1 minute

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IL6 Rabbit pAb

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