IL6 Rabbit pAb

216576

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S216576

Product Name: Anti-IL6 Rabbit Polyclonal Antibody

Synonyms: CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2

UNIPROT ID: P05231 (Gene Accession - BC015511 )

Background: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).

Immunogen: Fusion protein of human IL6

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 500-2000;ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cardiovascular,Cancer,Metabolism,Neuroscience,Immunology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216576(IL6 Antibody) at a dilution of 1/50(Secreted).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216576(Anti-IL6 Antibody) at dilution 1/50.
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 216576(Anti-IL6 Antibody) at a dilution of 1/50.	In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D220828(Anti-IL6 Antibody) at dilution 1/50.
Gel: 12%SDS-PAGE, Lysate: 40 μg; Lane 1-5: HUVEC, K562, Jurkat, Raji, 231 cell lysates; Primary antibody: 216576(IL6 Antibody) at dilution 1/400; Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution; Exposure time: 20 seconds

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IL6 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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