CD27 Rabbit pAb

217262

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S217262

Product Name: Anti-CD27 Rabbit Polyclonal Antibody

Synonyms: T14; S152; Tp55; TNFRSF7; S152. LPFS2

UNIPROT ID: P26842 (Gene Accession - BC012160 )

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Immunogen: Fusion protein of human CD27

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 1000-5000;ELISA: 2000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cancer, Immunology, Stem Cells

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217262(CD27 Antibody) at a dilution of 1/60(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217262(Anti-CD27 Antibody) at dilution 1/60.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 217262(Anti-CD27 Antibody) at a dilution of 1/60.	In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with fusion protein and then with D222070(Anti-CD27 Antibody) at dilution 1/60.
Gel: 10%SDS-PAGE, Lysate: 40 μg; Lane 1-3: Raji cells, PC3 cells, lovo cells; Primary antibody: 217262(CD27 Antibody) at dilution 1/727; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 1 minute

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CD27 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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