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Nicastrin Rabbit mAb

262609

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Product Description Reference citations(0) Related Products
Cat.#:   N262609
Product Name:   Anti-Nicastrin Rabbit Monoclonal Antibody
Synonyms:   APH2; Ncstn; NCT; Nicastrin
UNIPROT ID:   Q92542
Background:    Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
Immunogen:    A synthetic peptide of human Nicastrin
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R02-9E6
MW:    Calculated MW: 78 kDa; Observed MW: 110-120 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    NeuroscienceyyyyyAlzheimer's disease
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Nicastrin in K562, rat Brain, 3T3, Hela lysates using Nicastrin antibody.
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