p53 Rabbit mAb

262658

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262658

Product Name: Anti-p53 Rabbit Monoclonal Antibody

Synonyms: TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

UNIPROT ID: P04637

Background: Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Immunogen: Recombinant protein of human p53

Applications: WB,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R07-6A7

MW: Calculated MW: 44 kDa; Observed MW: 53 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Hypoxia Signal Transductionyyyyy Hypoxia-Inhibition

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of p53 (green) in MCF-7 using p53 antibody,and DAPI(blue)

Western blot analysis of p53 in Jurkat lysates using p53 antibody.

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