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PUMA Rabbit mAb

262785

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N262785
Product Name:   Anti-PUMA Rabbit Monoclonal Antibody
Synonyms:   BBC3; PUMA; Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis
UNIPROT ID:   Q9BXH1
Background:    Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Immunogen:    A synthetic peptide of human PUMA
Applications:    WB,IHC-F,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-9C7
MW:    Calculated MW: 21 kDa; Observed MW: 21 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    apoptosis - Bcl-2 family
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of PUMA in Jurkat, THP-1, C6, 3T3, Hela lysates using PUMA antibody

Immunocytochemistry analysis of PUMA (green) in 293T using PUMA antibody,and DAPI(blue).

Western blot analysis of PUMA in K562 lysates using PUMA antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using PUMA antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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