Semaphorin 4D Rabbit mAb

262881

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262881

Product Name: Anti-Semaphorin 4D Rabbit Monoclonal Antibody

Synonyms: CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G

UNIPROT ID: Q92854

Background: Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Immunogen: A synthetic peptide of human Semaphorin 4D

Applications: WB,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R05-2E3

MW: Calculated MW: 96 kDa; Observed MW: 120 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Immunology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Semaphorin 4D/CD100 in Jurkat lysates using Semaphorin 4D/CD100 antibody.

Immunocytochemistry analysis of Semaphorin 4D (green) in Jurkat using Semaphorin 4D antibody,and DAPI(blue).

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Semaphorin 4D Rabbit mAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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