SSX2IP Rabbit mAb

262936

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262936

Product Name: Anti-SSX2IP Rabbit Monoclonal Antibody

Synonyms: ADIP; hMsd1

UNIPROT ID: Q9Y2D8

Background: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin . Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling . Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449).

Immunogen: A synthetic peptide of human SSX2IP

Applications: WB,IHC-F,IHC-P,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R02-5B6

MW: Calculated MW: 71 kDa; Observed MW: 71 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human,Rat

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Tags & Cell Markers

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of SSX2IP in Jurkat, Hela lysates using SSX2IP antibody	Immunocytochemistry analysis of SSX2IP (green) in K562 using SSX2IP antibody,and DAPI(blue).
Western blot analysis of SSX2IP in rat kidney lysates using SSX2IP antibody.	Immunohistochemistry analysis of paraffin-embedded Human Brain using SSX2IP antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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SSX2IP Rabbit mAb

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