Phospho-IRE1 (Ser724) Rabbit mAb

263172

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263172

Product Name: Anti-Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody

Synonyms: ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a

UNIPROT ID: O75460

Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser724 of human IRE1

Applications: WB,IP

Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R05-6E7

MW: Calculated MW: 110 kDa; Observed MW: 110 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Phosphorylated

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-IRE1 (Ser724) in MCF-7, HL-60 lysates using Phospho-IRE1 (Ser724) antibody.

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Phospho-IRE1 (Ser724) Rabbit mAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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