Cofilin Rabbit mAb

263276

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263276

Product Name: Anti-Cofilin Rabbit Monoclonal Antibody

Synonyms: CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform

UNIPROT ID: P23528

Background: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

Immunogen: A synthetic peptide of human Cofilin

Applications: WB,IHC-F,IHC-P,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R06-2C0

MW: Calculated MW: 19 kDa; Observed MW: 19 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Cofilin (green) in hela using Cofilin antibody,and DAPI(blue)	Western blot analysis of Cofilin in A549, MCF-7, 293T lysates using Cofilin antibody.
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Cofilin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Cofilin Rabbit mAb

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