Human GRM2 Full Length Protein

11116

Size：50 μg Price：$ 4400 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11116

Product Name: Human GRM2 Full Length Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: GLUR2; GPRC1B; mGlu2; MGLUR2

Target: GRM2

UNIPROT ID: Q14416

Description: Human GRM2 full length protein-synthetic nanodisc

Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Species/Host: HEK293

Molecular Weight: The human full length GRM2 protein has a MW of 95.6 kDa

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

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Human GRM2 Full Length Protein

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

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