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Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11213 | ||
Product Name: Human TACI Protein | ||
Size : 10 µg, 50 µg and 100 µg | ||
Synonyms: CD267;ACI;NFRSF13B | ||
Target: TACI | ||
UNIPROT ID: O14836 | ||
Description: Recombinant human TACI Protein with C-terminal Human Fc tag | ||
Background: The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. | ||
Species/Host: HEK293 | ||
Molecular Weight: The protein has a predicted molecular mass of 44.5 kDa after removal of the signal peptide.The apparent molecular mass of TACI-hFc is approximately 33-53 kDa due to glycosylation. | ||
Molecular Characterization: TACI(Ser2-Thr166) hFc(Glu99-Ala330) | ||
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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