Human NKp30 Protein, hFc Tag

11201

Size：100 μg Price：$ 525 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: 11201

Product Name: Human NKp30 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: NCR3;D337;Kp30;C7;Y117;ALS

Target: NKp30

UNIPROT ID: O14931

Description: Recombinant human NKp30 protein with C-terminal human Fc

Background: The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 39.0 kDa after removal of the signal peptide.The apparent molecular mass of NKp30-hFc is approximately 45-60 kDa due to glycosylation.

Molecular Characterization: NKp30(Leu19-Glu135) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human NKp30 Protein, hFc Tag on SDS-PAGE under reducing condition.	Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human B7H6, His tagged protein 11313 can bind Human NKp30, hFc tagged protein (11201) in a linear range of 250-2000 ng/ml.
Figure 3. B7H6 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with 2ug/ml Human NKp30 Protein, hFc Tag (11201) on Expi293 cells transfected with human B7H6 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

Reference citations

No data available

Product Targets

Product Categories

Human NKp30 Protein, hFc Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

Contant Us