Human EPHA3 Protein, mFc-His Tag

11171

Size：100 μg Price：$ 479 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11171

Product Name: Human EPHA3 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: TYRO4;HEK4;ETK1;ETK;EK4;HEK

Target: EPHA3

UNIPROT ID: P29320

Description: Recombinant human EPHA3 protein with C-terminal mouse Fc and 6xHis tag

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 85.9 kDa after removal of the signal peptide.

Molecular Characterization: EPHA3(Glu21-Gln541) mFc(Pro99-Lys330) 6×His tag

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human EPHA3 Protein, mFc-His Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human EPHA3, mFc-His tagged protein (11171) can bind Anti-EPHA3 Neutralizing antibody 28028 in a linear range of 0.13-16.0 ng/ml.

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Human EPHA3 Protein, mFc-His Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

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