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Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11262 |
Product Name: Human MERTK Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: MER;RP38;c-Eyk;c-mer;Tyro12 |
Target: MERTK |
UNIPROT ID: Q12866 |
Description: Recombinant human MERTK Protein with C-terminal 10xHis tag |
Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 54.0 kDa after removal of the signal peptide. |
Molecular Characterization: MERTK(Ala21-Ile505) 10×His tag |
Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human MERTK Protein, His Tag on SDS-PAGE under reducing condition. |
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