Human TNFRSF10B Protein, mFc Tag

11277

Size：100 μg Price：$ 445 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: 11277

Product Name: Human TNFRSF10B Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: TNFRSF10B;RAILR2;RAIL-R2;D262;R5;ILLER;RICK2;TNFR9;RICKB

Target: TNFRSF10B

UNIPROT ID: O14763

Description: Recombinant human TNFRSF10B protein with C-terminal 6xHis tag

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 40.5 kDa after removal of the signal peptide.

Molecular Characterization: TNFRSF10B (Ile56-Glu186) mFc(Pro99-Lys330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human TNFRSF10B Protein, mFc Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TNFRSF10B, mFc tagged protein (11277) can bind Anti-TNFRSF10B Neutralizing antibody 28041 in a linear range of 3.2-80 ng/ml.

Reference citations

No data available

Product Targets

Product Categories

Human TNFRSF10B Protein, mFc Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

Contant Us