Human TIGIT Protein, mFc Tag

11308

Size：100 μg Price：$ 445 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: 11308

Product Name: Human TIGIT Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: TIGIT;SIG9;STM3

Target: TIGIT

UNIPROT ID: Q495A1

Description: Recombinant human TIGIT Protein with C-terminal mouse Fc tag

Background: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 39.24 kDa after removal of the signal peptide.The apparent molecular mass of TIGIT-mFc is approximately 40-53 kDa due to glycosylation.

Molecular Characterization: TIGIT(Met22-Pro141) mFc(Pro99-Lys330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human TIGIT Protein, mFc Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TIGIT, mFc tagged protein (11308) can bind Anti-TIGIT Neutralizing antibody 28033 in a linear range of 0.13-16.0 ng/ml.

Reference citations

No data available

Product Targets

Product Categories

Human TIGIT Protein, mFc Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

Contant Us