Human AXL Protein, mFc Tag

11333

Size：100 μg Price：$ 479 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: 11333

Product Name: Human AXL Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: AXL;FO

Target: AXL

UNIPROT ID: P30530

Description: Recombinant Human AXL with C-terminal mouse Fc tag

Background: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 72.0 kDa after removal of the signal peptide.The apparent molecular mass of AXL-mFc is approximately 100-130 kDa due to glycosylation.

Molecular Characterization: AXL(Ala26-Pro449) mFc(Pro99-Lys330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human AXL Protein, mFc Tag on SDS-PAGE under reducing condition.

Reference citations

No data available

Product Targets

Product Categories

Human AXL Protein, mFc Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

Contant Us