Human FZD4 Protein, hFc Tag

11414

Size：100 μg Price：$ 415 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: 11414

Product Name: Human FZD4 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: CD344;EVR1;FEVR;Fz-4;Fz4;FZD4S;FzE4;GPCR;hFz4

Target: FZD4

UNIPROT ID: Q9ULV1

Description: Recombinant Human FZD4 with C-terminal human Fc tag

Background: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 42.4 kDa after removal of the signal peptide. The apparent molecular mass of FZD4-hFc is approximately 55-70 kDa due to glycosylation.

Molecular Characterization: FZD4(Phe37-Glu180) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human FZD4 Protein, hFc Tag on SDS-PAGE under reducing condition.

Reference citations

No data available

Product Targets

Product Categories

Human FZD4 Protein, hFc Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

Contant Us