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Human EREG Protein, hFc Tag

11413

Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     11413
Product Name:   Human EREG Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Ep;EPR;ER
Target:    EREG
UNIPROT ID:    O14944
Description:    Recombinant Human EREG with C-terminal human Fc tag
Background:     This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues. [provided by RefSeq, Jul 2015]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of EREG-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    EREG(Val63-Leu108) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human EREG Protein, hFc Tag on SDS-PAGE under reducing condition.
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