Human IL11RA Protein, hFc Tag

11377

Size：100 μg Price：$ 479 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11377

Product Name: Human IL11RA Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: IL-11 R alpha;L-11 RA;L11RA;nterleukin-11 receptor subunit alpha;L-11 receptor subunit alpha;L-11R subunit alpha;L-11R-alpha

Target: IL11RA

UNIPROT ID: Q14626

Description: Recombinant Human IL11RA with C-terminal human Fc tag

Background: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of IL11RA-hFc is approximately 35-55 kDa due to glycosylation.

Molecular Characterization: IL11RA(Ser24-Ala370) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL11RA Protein, hFc Tag on SDS-PAGE under reducing condition.

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Human IL11RA Protein, hFc Tag

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