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Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11500 |
Product Name: Human DAP10 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: HCST;KAP10;PIK3AP |
Target: DAP10 |
UNIPROT ID: Q9UBK5 |
Description: Recombinant human DAP10 protein with C-terminal human Fc tag |
Background: This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 29.1 kDa after removal of the signal peptide. The apparent molecular mass of DAP10-hFc is approximately 25-55 kDa due to glycosylation. |
Molecular Characterization: DAP10(Gln19-Pro48) hFc(Glu99-Ala330) |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human DAP10 Protein, hFc Tag on SDS-PAGE under reducing condition. |
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