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Human RNASE4 Protein, hFc Tag

11475

Size:100 μg Price:$ 445 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     11475
Product Name:   Human RNASE4 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   RAB1;RNS4
Target:    RNASE4
UNIPROT ID:    P34096
Description:    Recombinant human RNASE4 protein with C-terminal human Fc tag
Background:     The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2013]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 40 kDa after removal of the signal peptide.The apparent molecular mass of RNASE4-hFc is approximately 40-55 kDa due to glycosylation.
Molecular Characterization:    RNASE4(Gln29-Gly147) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human RNASE4 Protein, mFc Tag on SDS-PAGE under reducing condition.
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