Human IL31 Protein, hFc Tag

11528

Size：100 μg Price：$ 389 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11528

Product Name: Human IL31 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: Interleukin-31;L-31

Target: IL31

UNIPROT ID: Q6EBC2

Description: Recombinant human IL31 protein with C-terminal human Fc tag

Background: IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 42 kDa after removal of the signal peptide. The apparent molecular mass of IL31-hFc is approximately 35-55 kDa due to glycosylation.

Molecular Characterization: IL31(Ser24-Thr164) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL31 Protein, hFc Tag on SDS-PAGE under reducing condition.

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Human IL31 Protein, hFc Tag

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