Human FLT1 Protein, His Tag

11516

Size：100 μg Price：$ 659 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: 11516

Product Name: Human FLT1 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: VEGFR-1;Tyrosine-protein kinase FRT;FLT-1;FLT;Vascular permeability factor receptor

Target: FLT1

UNIPROT ID: P17948

Description: Recombinant human FLT1 protein with C-terminal 6xHis tag

Background: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 83.0 kDa after removal of the signal peptide. The apparent molecular mass of FLT1-His is approximately 100-130 kDa due to glycosylation.

Molecular Characterization: FLT1(Ser27-Asn756) 6×His tag

Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human FLT1 Protein, His Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human FLT1 Protein, His Tag (11516) can bind Anti-FLT1 Neutralizing antibody 28126 in a linear range of 0.92-234.38 ng/mL.

Reference citations

No data available

Product Targets

Product Categories

Human FLT1 Protein, His Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

Contant Us