Human STAB1 Protein, hFc Tag

11508

Size：100 μg Price：$ 415 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11508

Product Name: Human STAB1 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: Stabilin-1;FEEL-1;MS-1 antigen

Target: STAB1

UNIPROT ID: Q9NY15

Description: Recombinant human STAB1 protein with C-terminal human Fc tag

Background: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq, Jul 2008]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 66.7 kDa after removal of the signal peptide. The apparent molecular mass of STAB1-hFc is approximately 70-100 kDa due to glycosylation.

Molecular Characterization: STAB1(Asp638-Leu1024) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human STAB1 Protein, hFc Tag on SDS-PAGE under reducing condition.

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Human STAB1 Protein, hFc Tag

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