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Size:100 μg Price:$ 569 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11579 |
Product Name: Human LTBR Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: TNF-RIII;TNFR-III;TNFR3;TNFRSF3 |
Target: LTBR |
UNIPROT ID: P36941 |
Description: Recombinant human LTBR protein with C-terminal human Fc tag |
Background: This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 47.9 kDa after removal of the signal peptide. The apparent molecular mass of LTBR-hFc is approximately 55-70 kDa due to glycosylation. |
Molecular Characterization: LTBR(Gln31-Met227) hFc(Glu99-Ala330) |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human LTBR Protein, hFc Tag on SDS-PAGE under reducing condition. |
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