Human IFNA1 Protein, hFc Tag

11573

Size：100 μg Price：$ 550 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11573

Product Name: Human IFNA1 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: IFN-alpha-1/13;LeIF D;IFNA13

Target: IFNA1

UNIPROT ID: P01562

Description: Recombinant human IFNA1 protein with C-terminal human Fc tag

Background: This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia. [provided by RefSeq, Aug 2020]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 45.5 kDa after removal of the signal peptide. The apparent molecular mass of IFNA1-hFc is approximately 35-55 kDa due to glycosylation.

Molecular Characterization: IFNA1(Cys24-Glu189) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IFNA1 Protein, hFc Tag on SDS-PAGE under reducing condition.

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Product Categories

Human IFNA1 Protein, hFc Tag

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