Human ITGB7 Protein, hFc Tag

11648

Size：100 μg Price：$ 415 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11648

Product Name: Human ITGB7 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: integrin;beta 7;integrin beta 7 subunit

Target: ITGB7

UNIPROT ID: P26010

Description: Recombinant human ITGB7 protein with C-terminal human Fc tag

Background: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 105.16 kDa after removal of the signal peptide.

Molecular Characterization: ITGB7 (Glu20-His723) hFc (Glu99-Ala330) co-translates with ITGAE (Phe19-Ser1124) hFc (Glu99-Ala330).

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

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Product Categories

Human ITGB7 Protein, hFc Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

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