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Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11670 |
Product Name: Human CB2 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: CB-2;CB2;CX5 |
Target: CB2 |
UNIPROT ID: P34972 |
Description: Recombinant Human CB2 Protein with C-terminal human Fc tag |
Background: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 33.9 kDa after removal of the signal peptide.The apparent molecular mass of CB2-hFc is approximately 35-55 kDa due to glycosylation. |
Molecular Characterization: CB2(Met1-Lys33) (Asn93-Ala104) (Thr173-Asn188) (Ala270-Lys278) hFc(Glu99-Ala330) |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human CB2 Protein, hFc Tag on SDS-PAGE under reducing condition. |
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