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Size:100 μg Price:$ 415 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11701 |
Product Name: Human LGALS3 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: CBP35;GAL3;GALBP;GALIG;L31;LGALS2;MAC2 |
Target: LGALS3 |
UNIPROT ID: P17931 |
Description: Recombinant Human LGALS3 Protein with C-terminal 6xHis tag |
Background: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 26.9 kDa after removal of the signal peptide.The apparent molecular mass of LGALS3-His is approximately 25-35 kDa due to glycosylation. |
Molecular Characterization: LGALS3(Ala2-Ile250) 6×His Tag |
Purity: The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human LGALS3 Protein, His Tag on SDS-PAGE under reducing condition. |
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