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Human CD6 Protein, His Tag

11728

Size:100 μg Price:$ 415 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     11728
Product Name:   Human CD6 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   TP120
Target:    CD6
UNIPROT ID:    P30203
Description:    Recombinant human CD6 protein with C-terminal 6xHis tag
Background:     This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 41.4 kDa after removal of the signal peptide. The apparent molecular mass of CD6-His is approximately 55-100 kDa due to glycosylation.
Molecular Characterization:    CD6(His18-Glu398) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD6 Protein, His Tag on SDS-PAGE under reducing condition.
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