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Human IL20 Protein, hFc Tag

11756

Size:100 μg Price:$ 415 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     11756
Product Name:   Human IL20 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   IL-20;Cytokine Zcyto10
Target:    IL20
UNIPROT ID:    Q9NYY1
Description:    Recombinant human IL20 Protein with C-terminal Human Fc tag
Background:     The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 43.7 kDa after removal of the signal peptide. The apparent molecular mass of IL20-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    IL20(Leu25-Glu176) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL20, hFc Tag on SDS-PAGE under reducing condition.
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