Human TIE2 Protein, hFc Tag

11747

Size：100 μg Price：$ 415 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: 11747

Product Name: Human TIE2 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: CD202B;GLC3E;TIE-2;TIE2;VMCM;VMCM1

Target: TIE2

UNIPROT ID: Q02763

Description: Recombinant human TIE2 protein with C-terminal human Fc tag

Background: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 105.38 kDa after removal of the signal peptide.

Molecular Characterization: TIE2 (Trp23-Leu748) hFc(Glu99-ALA330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Reference citations

No data available

Product Targets

Product Categories

Human TIE2 Protein, hFc Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

Contant Us