Human OSMR Protein, His Tag

11782

Size：100 μg Price：$ 659 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11782

Product Name: Human OSMR Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: IL-31R-beta;IL-31RB;OSMRB;OSMRbeta;PLCA1

Target: OSMR

UNIPROT ID: Q99650

Description: Recombinant human OSMR protein with C-terminal 6xHis tag

Background: This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 81.9 kDa after removal of the signal peptide. The apparent molecular mass of OSMR-His is approximately 100-250 kDa due to glycosylation.

Molecular Characterization: OSMR(Glu28-Met740) 6×His tag

Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human OSMR Protein, His Tag on SDS-PAGE under reducing condition.

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Human OSMR Protein, His Tag

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