Human CCR2 Protein, mFc Tag

11777

Size：100 μg Price：$ 569 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: 11777

Product Name: Human CCR2 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: CC-CKR-2;MCP-1-R;CD192

Target: CCR2

UNIPROT ID: P41597

Description: Recombinant human CCR2 protein with C-terminal mouse Fc tag

Background: The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 31.1 kDa after removal of the signal peptide. The apparent molecular mass of CCR2-mFc is approximately 35-55 kDa due to glycosylation.

Molecular Characterization: CCR2(Met1-Ala42) mFc(Pro99-Lys330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CCR2 Protein, mFc Tag on SDS-PAGE under reducing condition.

Reference citations

No data available

Product Targets

Product Categories

Human CCR2 Protein, mFc Tag

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

Contant Us