Human BTC Protein, hFc Tag

11894

Size：100 μg Price：$ 389 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11894

Product Name: Human BTC Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: Betacellulin

Target: BTC

UNIPROT ID: P35070

Description: Recombinant Human BTC Protein with C-terminal human Fc tag

Background: This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients. [provided by RefSeq, Nov 2015]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 35.1 kDa after removal of the signal peptide. The apparent molecular mass of BTC-hFc is approximately 35-70 kDa due to glycosylation.

Molecular Characterization: BTC(Asp32-Tyr111) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human BTC Protein, hFc Tag on SDS-PAGE under reducing condition.

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Human BTC Protein, hFc Tag

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