Human SIGLEC5 Protein, His Tag

11882

Size：100 μg Price：$ 415 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11882

Product Name: Human SIGLEC5 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: CD33L2;CD170;OB-BP2;OBBP2;SIGLEC-5

Target: SIGLEC5

UNIPROT ID: O15389

Description: Recombinant Human SIGLEC5 Protein with C-terminal 6xHis tag

Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 47.2 kDa after removal of the signal peptide. The apparent molecular mass of SIGLEC5-His is approximately 55-100 kDa due to glycosylation.

Molecular Characterization: SIGLEC5(Glu17-Thr434) 6×His tag

Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human SIGLEC5 Protein, His Tag on SDS-PAGE under reducing condition.

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Human SIGLEC5 Protein, His Tag

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