Human GPNMB Protein, His Tag

11912

Size：100 μg Price：$ 389 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11912

Product Name: Human GPNMB Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: HGFIN;NMB;PLCA3

Target: GPNMB

UNIPROT ID: Q14956

Description: Recombinant Human GPNMB Protein with C-terminal 6xHis tag

Background: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 53.9 kDa after removal of the signal peptide. The apparent molecular mass of GPNMB-His is approximately 70-130 kDa due to glycosylation.

Molecular Characterization: GPNMB(Lys23-Met496) 6×His tag

Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human GPNMB Protein, His Tag on SDS-PAGE under reducing condition.

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Human GPNMB Protein, His Tag

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