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Size:100 μg Price:$ 415 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11908 |
Product Name: Human LY6H Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: NMLY6 |
Target: LY6H |
UNIPROT ID: O94772 |
Description: Recombinant Human LY6H Protein with C-terminal human Fc tag |
Background: Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.[UniProtKB/Swiss-Prot Function] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of LY6H-hFc is approximately 35-55 kDa due to glycosylation. |
Molecular Characterization: LY6H(Leu26-Gly115) hFc(Glu99-Ala330) |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1.Human LY6H Protein, hFc Tag on SDS-PAGE under reducing condition. |
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